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National Repository of Grey Literature

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Characterisation of novel serpin TILIr and its relatives from the superfamily of serine protease inhibitors from \kur{Ixodes ricinus} tick SLABÁ, Hana Novel gene, named TILIr ( TIL Ixodes ricinus), that encoded yet unknown protein with TIL domain characteristic to proteins that belong to trypsin inhibitors family was discovered and isolated from hard tick Ixodes ricinus. Two isoforms of novel gene were identified and studied in this project. As the result of this study recombinant TILIr protein was produced in bacterial expression system and analysis of its functional characteristics was conducted. The protein belonging to family of trypsin inhibitors represent a potential candidate for anti-tick vaccine component. Detailed record

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